Vagus Nerve Stimulation Transiently Mitigates Chemotherapy-Induced Peripheral Neuropathy in Rats. Citation: (Zhang 2020)

Chemotherapy-induced peripheral neuropathy is a severe side effect of chemotherapeutic agents. Vagus nerve stimulation (VNS) attenuates neuro-inflammation by activating the cholinergic anti-inflammatory pathway and thus may attenuate CIPN.

CIAM note: Although this study focuses on direct VNS at the cervical vagus nerve, the research supports a relatively large body of research surrounding related to other VNS, as well as non-invasive transcutaneous auricular vagus nerve stimulation (taVNS), treatments; some of which are FDA approved (for surgical device implants), practiced in the field of neuro-functional auricular acupuncture (non-invasively), or applied in related approaches of Auricular Medicine (also non-invasively). Read the full paper at DovePress.

Reference: Zhang R, Gan Y, Li J, Feng Y. Vagus Nerve Stimulation Transiently Mitigates Chemotherapy-Induced Peripheral Neuropathy in Rats. DovePress. 2020:3457-3465


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