Transcutaneous Vagus Nerve Stimulation Modulates Default Mode Network in Major Depressive Disorder. Citation: (Fang 2016, 266-273)

Vagus nerve stimulation (VNS) is a Food and Drug Administration approved somatic treatment for drug-resistant epilepsy and depression. In vivo VNS systems, however, are an option limited to patients who have failed to respond to multiple treatment options. Transcutaneous VNS (tVNS) is a non-invasive method based on afferent/efferent vagus nerve distribution on the surface of the ear. The safe and low-cost characteristics of tVNS have the potential to significantly expand the clinical applicat...